The easiest way to be compliant with tax forms is by using Intuit Online Payroll via the QuickBooks Employees->Payroll menu. IOP does charge a monthly fee though. QuickBooks Mac will also work with Gusto (which also charges a monthly fee) as well as Intuit's Full Service Payroll (which also... you get the drift).
If you want to do it yourself you have to use the State of Virginia's resources. The W2 is usually similar to the Federal W2 you filed. States typically require not only W2s but also quarterly tax filings, payments, unemployment compensation, etc. All of these have to be filed in a timely manner (often after every paycheck).