Welcome to the Community, Shireen.
Thank you for reaching out. May I know the specific error message you're seeing when running your payroll? This will help us understand the issue better and ensure we provide the correct solution to your problem.
In the meantime, you can perform some basic troubleshooting steps. Refresh your browser, log out of QuickBooks Online Payroll, then log back in. You can also try using an incognito window to bypass cached data that may be causing the problem.
If you have any other questions, feel free to let me know. We're here to assist you.