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It's nice to see you again in the Community, @jrufo.
Yes, you can set up a vendor as a 1099 recipient in QuickBooks Online. I can help route you to this article for the overview: Common questions about 1099s.
It's also best to consult your accountant to verify the vendors that are qualified for 1099. To make a vendor eligible, here's how:
You may also refer to this article for more details: Add contractors or vendors when preparing 1099s.
The articles should help as a guide in preparing and filing 1099's for your vendors. If you have additional questions about the process, do let me know. I'll be here to help.