Certainly, but there are options. You really need someone experienced in this area to help you.
You have the option of going with the standard mileage deduction which was $0.56/mile in 2021 and increases to $0.585/mile in 2022. If you choose the standard mileage rate in the first year of vehicle use, you can choose either the standard mileage rate or the actual expense method in future years. It may be helpful to figure your deduction both ways and see which saves you more.
Alternatively, you can go with the actual expense method which allows you to deduct the actual expenses associated with owning the vehicle in proportion to the mileage driven for business vs. personal use. For example, if you use the vehicle 60% of the time for business, you can deduct 60% of the actual expenses - depreciation, payments, license tabs/registration fee, oil, gas, repairs, tires, etc. It gets trickier when it comes to depreciation. Section 179 depreciation allows a larger first-year deduction (up to $18,200 X percentage of business use). But, you must take Section 179 the first year the vehicle is placed in service (2021) or you can't ever take it. If you go that route, make sure you're aware of depreciation recapture so that you're not surprised by owing tax when you sell the vehicle in the future. Again, I would suggest getting your own tax advice on this, it could potentially save you thousands in tax - especially if the vehicle is new and used primarily for business purposes. Here are a few links for your reading pleasure: