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Good day, stedder52.
We're unable to create an invoice from a PO in QuickBooks Online. It''s usually used for vendors and expenses.
If the customer's PO was recorded as an estimate in your account, follow these steps on how to start an invoice from it:
If not, then you just have to click the + New button in the upper-left hand corner of QBO, then select Invoice.
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Please know that you can always reply below if you have follow-up questions. We're always here to guide and assist you while working in QuickBooks.