Thank you for posting here in the Community. The ads in QuickBooks are designed to guide and suggest you how to optimize your QuickBooks Online (QBO) experience. Since they're affecting your navigation experience, I recommend clicking on the X or No, thanks button. This will prevent the pop-ups from showing up again.
Once done, you now create an invoice to your customer. Let me guide you how:
You can press the Esc button on your keyboard if you were unable to see these options on your screen.
If the issue persists, I recommend performing some troubleshooting steps that can help to isolate this. To start, log into your QuickBooks Online account using a private browser. Your regular browser's internet files might have caused this unexpected behavior while using QuickBooks.
Open a supported browser, and follow the specific hotkey: