Hi there, ArrowheadPT.
Sales tax in QuickBooks Online is automatically calculated based on the following:
- Your customer’s tax-exempt status
- Where you sell and where you ship
- What you sell
In some states, when you sell or ship to a different address, sellers are required to charge sales tax based on business location.
For your situation, you'll want to manually change the Location of sale on each transaction with a different address. This will update the sales tax calculation in the transaction. Here's a sample screenshot of an invoice for a visual guide:

The following articles also include more information about automated sales tax:
I'm a post away if you need more help with QuickBooks Online. Thanks.