The only 2 part supported is preprinted forms. And the 4 part used to offer both styles but this year only the 4 corner style.
Despite the law from the IRS that says bank paper MUST be perforated, consider this - I doubt even one of your employees files a paper form. H&R Block, TurboTax, everything is digita nad none of them require sending in a paper form (I printed 4 part on plain paper)