Hi there, outercircleinc. 

With Payroll for QuickBooks Online, federal and state payroll taxes are instantly calculated. Conveniently you can set up and pay federal and select state taxes electronically with E-Pay. Though, some agencies require you to enroll before you start using E-Pay.  To learn more the latest payroll updates in QuickBooks, please visit this link: Payroll 101. 

 For additional information about this, I recommend checking these articles:  

• File quarterly tax forms 
• Payroll Tax Compliance Links  
• Enroll in E-File & Pay 

Let me know if there's anything else that I can help with your account. I'm always here to assist. Have a great rest of the day!