Thanks for posting a question here in the Community, @WardPro.
Due to the latest updates, some third-party apps may be disabled in QuickBooks Desktop (QBDT). This is the same case with your AutoHotkey app.
We can perform some steps to help fix this. First, let's ensure the app has full access to your company file. To verify this, here's how:
However, if everything's fine, you may consider contacting an IT guy from the AutoHotkey app. This way, they can check if it can be integrated with your QuickBooks and do some modifications if needed.
Also, you'll want to learn more on how to do a clean install in QuickBooks Desktop (QBDT) to fix company file issues. Here's an article that you can refer to: How to clean install QBDT?.
Fill me in if you have more questions about managing third-party apps in QBDT. I'll be always here to help. Stay safe, @WardPro.