Hi there, @Tig.
I'm here to help share some details about handling 1099 Direct Deposit in QuickBooks Desktop.
To pay by Direct Deposit, the pay date must not be less than two business days in the future. That said, yes, you can send your 1099's Direct Deposit but make sure to enter the correct date that the independent contractor should be paid.
Here are some great articles that you can check out about paying Independent Contractors using Direct Deposit and fixing transmission issues:
If you need further assistance with this process, feel free to get in touch with our Customer Care Team.
In the event that you should have questions about this, or need anything else concerning QuickBooks, you can find me here. Take care and enjoy your vacation, Tig.