Hey there, kpvs.
Thanks for reaching out to the Community for support. I'd be happy to help.
QuickBooks Online Payroll provides the option to run unscheduled pay runs. I recommend taking a look at this article for more details and instructions on how to proceed. Once you've created the final pay cheque, you can terminate your employee and create an ROE.
If you have any other questions please don't hesitate to reach back out here.