Hi ocvinson,
It's essential that you're able to access the tools you need when using the payroll center in QuickBooks Desktop. I can see how the unrecoverable error you're receiving when selecting e-payments can be of concern. I'd like to steer you in the right direction to get this resolved as soon as possible. I recommend contacting QuickBooks Desktop U.S. support. They'll have the ability to look deeper into this with you and help you reach your goal. I hope this helps!
Take care and enjoy the rest of your day!