Hello, @lsefcik.
I'll help you out in voiding the check without impacting the AP, cash, and expense balance in QuickBooks Online.
The easiest way that I can think of right now is to enter a deposit in the current fiscal period for the same amount to the same account as the original check. Then after that, clear both (they will cancel each other out).
See the sample screenshot below for your reference:

You can check these articles for more insights about reconciliation:
Please know I'm always available here for all of your questions and concerns. Keep safe!