Hello there, Susan.
It seems like you're referring to QuickBooks Online (QBO) keyboard shortcut keys that won't work on your Chrome browser.
In QBO, most keyboard shortcuts are designed to work across different browsers with some exceptions due to Chrome browser's built-in shortcuts and browser-specific behavior.
The sole exceptions for specific functions you wish to execute in QBO while using a Chrome browser occur when you attempt to open a second window, conduct a text search within a window, or save forms. You can use this article to learn more about this Chrome exception: Keyboard shortcuts for QuickBooks Online.
As an alternative, you can access the keyboard shortcut keys for the Chrome browser by simultaneously pressing Ctrl + Alt + ?.
You can always get back to the Community space if there's anything else you need to know aside from keyboard shortcut keys. I'm here to help you.