Payroll doesn't without payroll taxes about 2 or 3 paychecks

This isn't the kind of service we'd want to your experience, Barbara. I'm here to provide you with several reasons why payroll taxes are not being taken out of paychecks when running payroll.

There are various reasons why payroll taxes aren't taken out any taxes, it's either the total annual salary exceeds the salary limit or the gross wages of the employee's payroll are too low.

Before running payroll in QuickBooks Desktop, it's recommended to update QuickBooks to the latest release and ensure you'll have an updated tax table. You can use this article as your reference in updating your payroll tax table: Get the latest tax table update.

After running the payroll update, you'll have to refresh the paychecks by reverting them.

Additionally, you can check out this article for more troubleshooting solutions when payroll taxes are not withheld: Troubleshoot paychecks calculating incorrectly in QuickBooks Desktop Payroll.

For future reference, we also have a variety of reports you can pull up in QuickBooks Online Payroll in case you need help checking up on your employees' data and other payroll-related concerns: Run payroll reports.

You can always get back to me if you still have questions about calculating payroll taxes or anything else by leaving a reply below. Stay safe and have a wonderful day!

I have done all that.  I researched the issue and tried every possible solution that has been wrote. 

I appreciate you for returning to the thread, Barbara. 

I'm here to route you to our Support Team for live assistance in identifying what's causing QuickBooks Desktop (QBDT) to not take out taxes from the paychecks created. 

Since you've performed the potential fixes to resolve the issue and it persists, it would be best to contact our Support Team. They offer live assistance and have the necessary tools to help in the troubleshooting process. Here's how to contact them: 

1. Go to Help in your QBDT. Then, select QuickBooks Desktop Help/Contact Us.
2. Select Contact Us.
3. Give a brief description of the issue. Then, choose Continue.
4. Sign in to your Intuit account. Then, click on Continue and then Continue with my account.
5. Select to chat with us or Have us call you.

For Pro, Premier, and Plus, our team is available from Monday through Friday from 6 AM to 6 PM PT. For Enterprise, support is available any time and any day. 

If you need to correct YTD wages, taxes, and deduction items in the future, I'm adding this article as a reference: Adjust payroll liabilities in QuickBooks Desktop Payroll. 

We'll be here in the Community if you have further updates on your concern about QBDT not calculating taxes for your employees' paychecks. We'll do our best to assist.

Thank you, I will try this when I run the next payroll on the 15th.

Thank you; I will try this when I run the next payroll on the 15th.