I'll share some information about editing transactions in QuickBooks Online, Kitkat2.
An estimate is a non-posting sales transaction. And any changes that you'll make shouldn't affect your books. However, QuickBooks will always warn you or give you notice every time you'll make any changes since you've already created an invoice out from your estimate. Plus the fact that you've already closed your books for the year 2021. This is to ensure the accuracy of your book's finances.
But even if you're getting the notice, you still have the option of whether or not to edit your estimates. I recommend reaching out to your accountant to double-check if any changes that you'll make will give a great impact on your company's finances.
Furthermore, QuickBooks provides dozens of reports that will tell you the different aspects of your business. Learn how to run reports through this article to know the details of your company's information: Run Reports In QuickBooks Online.
If there's anything else that you need, let me know so I can get back to you as soon as possible. I'll just be one post away if you need help.