I can share some information about file attachments, @JRRubin1.
I suggest putting your file attachments to where your company file for QuickBooks Desktop 2021 is located.
Are you referring to those attachments that you've added to your transactions? If so, I suggest putting your file attachments to where your company file for QuickBooks Desktop 2021 is located. An Attach folder is created and stored in the same location as the QuickBooks company file.
Renaming or moving the company file to a different location will break the connection between the Attached Documents and company file.
Check this article for more information: QuickBooks Document Center: FAQs and common issues.
Let me know if you still have questions about your company file. I'm always here to assist. Have a wonderful day!