Hi there, @burnshomeandrepa.
QuickBooks Self-Employed (QBSE) automatically calculates home office deductions depends on its recorded size. The program calculates your home office deduction in 2 ways, the simplified method and actual expenses method.
To learn more about home office deduction, feel free to check out this article for more information: The Home Office Deduction.
You might also want to read this article to know more about home off expenses: Schedule C: Home office expenses.
Please let me know if you need clarification about this, or there's anything else I can do for you. I'll be standing by for your response. Have a great day and stay safe.