Yes, QuickBooks Desktop (QBDT) 2021 is fully compatible with Windows 10, KLE24. I'll be pleased to add more details regarding this matter for clarification.

Windows 10 is compatible with QBDT 2021 across all editions, including 64-bit, natively installed. Using Windows natively instead of through an emulator or virtual environment is recommended to maximize your experience. For more information, refer to this material: System requirements for QuickBooks Desktop 2021.

On the other hand, while our team is working on the compatibility of QBDT 2021 in Windows 11 to address related issues, please know that we currently don't have the exact time frame for the implementation.

Moreover, you'll want to update your company file to keep it working with the new version of QBDT. You can scan this resource for the detailed process: Update your company files to a new version of QuickBooks Desktop.

If you have other queries about the compatibility of your operating system with QuickBooks Desktop, you can leave a comment in this thread through the Reply button below. We're here to help anytime you need a hand.