Hey thanks so much for your kind reply and for taking the time to help.  I have noticed that happen in the past when the page was zoomed too large, but that's not what it was this time. 

After trying several different browsers to no avail, I cleared the cache. While that didn't immediately help, after I re-booted my Mac everything now seems to be back to normal and the Save button is back!  Yay!!

Thank you again :)