I am having the same issues with the error message; but it only comes about when I am trying to e-file my State SUI payroll tax returns.  The issue has only occurred in 2022 version of QB's; I still use 2020 version for one client, and I had no problem.  I have also noticed if I try to create the Tax form worksheets or Local tax summary, I get to the security warning- Macros have been disabled; but there is no option to "enable".  When I click on options I get a "Security Alert - Macros" message - with a warning "The digital signature has been tampered with after the content was signed.  This content cannot be trusted."  Is this all related to the 32bit/64bit issue or could this be something else?  Thanks!