Greetings, drcconnolly.
Welcome to the Community space. Allow me to address your concern about the transactions you manually entered into QuickBooks.
Once you create and save transactions, you won’t need to enter them again. If you do, those transactions will be duplicated and will affect your books.
In case you’ve downloaded banking transactions, make sure to match them with the existing one you’ve manually created. To know more on how to match these transactions, check out this article: https://community.intuit.com/articles/1773491.
If there’s something else you need, feel free to reach out to me or post again in the Community. I’ll be around to help. Have a good day!