Quickbooks is randomly deleting lines from my entries when I try to delete a line (the trash can). Today, it deleted lines 48, 112, and 149 when I try to delete top line

The OP is correct.  QBO is deleting the wrong lines when users click the trash can.  It has happened to me numerous times today.  Example:  I have 8 lines of purchases entered that were populated from a precious transaction.  I go down through lines 1-5 and update the qty and price.  When I reach line I realize I did not order any of these do I click the trash can.  In my case, it always deletes line 1 no matter what trash can I click.

The Community has you covered, @WRECKROOM.

Issues like this are usually the result of outdated or corrupt cache files in your web browser. Browser caches help speed up basic browsing that allow you to save more time when loading repetitive images or information. However, it can impact processes and cause this unexpected behavior when your browser accumulates too much historical data. Not to worry, you can clear them in just a few easy steps.

In the meantime, we can start by accessing your account through an incognito window to rule out the possibility of a webpage issue. You can refer to these shortcut keys to open an incognito window in all supported browsers:

• Google Chrome: press Ctrl + Shift + N 

• Mozilla Firefox: press Ctrl + Shift + P

• Safari: press Command + Shift + N

Once logged in, go back and try to click the trash can again. If it works, go back to your regular browser and clear its cache to refresh the program. We advise our users to delete them now and then to prevent and fix issues like this.

However, if you get the same result while using a private browser, I recommend switching to a different browser.

Let me share some resources that you can browse and use as a reference in managing and navigating around your QuickBooks account.

• Video Tutorials for QuickBooks Online - You can watch videos that can help you perform the most vital features of the program. 

• Small Business Webinars and Trainings - Join our live QuickBooks webinars for more in-depth knowledge on how you can maximize the use of QuickBooks to manage your finances.

Please let me know in the comment section how it goes. I'm determined to ensure your success. Thanks for coming to the Community, I look forward to hearing from you again.

No offense, but this is the Intuit response to every user problem.  Clear your cache files!  I have done that, many times and I do it often as a matter of precaution.  There is a bug, sadly not uncommon for Quickbooks Online and will probable never get fixed but if you read my post carefully you can replicate the issue.  BTW, I have replicated the issue on 4 different computers now, so it is not my PC or my cache files.  I do thank you for answering.  It is appreciated even though I don't sound very appreciative.  Just very frustrated that I have to keep re-entering the first line because I forget not to "click away" before I click the trash can.

I wish I could make it better, @WRECKROOM. I want to ensure this problem is addressed timely.

Since the issue persists, I recommend contacting our Customer Care Support. You can work with one of our specialists in letting our engineering team investigate why random line items of your entries are deleted. I'll show you how.

1. Go to Help.
2. Select Search.
3. Click Contact Us.
4. Enter a few words describing how the line items are removed randomly in the What can we help you with? field.
5. Select Start a conversation or Have us call you.

I want to include that reaching out to our Customer Care Support is best during business hours from 6 AM-6 PM PT Monday-Friday.

I'm adding a relevant link to help you out with the preparation for the coming year-end:: Close the Year Smoothly and Get Ready for 2022.

Post again if you have other payroll forms concerns in QuickBooks Online. I'll be right here to help anytime. Take care always!

I'd like to add to this conversation.

It's not browser issue.

QBO needs to fix this deleting line issue for it is WASTING OUR TIME.  WERE YOU MAKING JOURNAL ENTRIES AT MIDNIGHT TO GET YOUR WORK DONE &  WITH QBO INCREASING YOUR TIME TO GET THINGS DONE BECAUSE IT IS DELETING WRONG LINES.

THIS ISSUE HAPPENS IN ALL BROWERS, WITH CACHE & BROWSING HISTORY CLEARED & IN AN INCOGNITO WINDOW.  QBO SUPPORT EVEN HAD THIS OCCUR TO THEM ON THEIR COMPUTER WHEN I CALLED TO COMPLAIN & THEY TRIED TO REPLICATE THE ISSUE.