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There are times when stored cache in your browser can cause unexpected behaviors.
To isolate this, I suggest you open your browser's private window.
Proceed to run payroll within the private window of your browser. If you're able to do so, go back to your regular browser and clear its cache. Otherwise, I suggest you use an alternative browser.
In case you encounter any possible browser issues in the future, you can keep this article for reference: Troubleshooting browser problems.
Place a reply in the comments below if you have other issues running payroll in QuickBooks Online. I'll get back to you as soon as I can.