Hello, markjacobs736. I'll provide you information about your concern.
Let's make sure that we're using the latest version of QuickBooks Desktop and downloaded the latest payroll tax table. That way, we can ensure that QBDT will calculate the taxes when processing payroll. You can check this article for the step by step process: Get the latest payroll tax table update.
Also, the payroll tax calculation is derived from the payroll data we've entered. For QuickBooks to calculate correct tax amounts, we also need to set up properly our payroll items.
Here are articles you can check to learn more about payroll taxes for your reference:
Please let me know if you need anything else with managing your payroll taxes.