Hi, @vtalsma.

I'm here to help you with installing your QuickBooks Desktop version on Windows 10 successfully.

To isolate the issue, I recommend downloading the QuickBooks Tool Hub to fix QuickBooks Desktop installation errors. First, download the QuickBooks Tool Hub.

1. Close QuickBooks.
2. Download the most recent version (1.4.0.0) of the QuickBooks Tool Hub. Save the file somewhere you can easily find it (like your Downloads folder or your Windows desktop).
3. Open the file you downloaded (QuickBooksToolHub.exe).
4. Follow the on-screen steps to install and agree to the terms and conditions.
5. When the install finishes, double-click the icon on your Windows desktop to open the tool hub.

Second, use the QuickBooks Install Diagnostic Tool.

1. Open the QuickBooks Tool Hub.
2. In the tool hub, select Installation Issues.
3. Select QuickBooks Install Diagnostic Tool. Let the tool run. It can take up to 20 minutes.
4. When the tool finishes, restart your computer.

Then, update your Windows to prevent and fix installation errors.

1. Check out Windows Update: FAQ on how to update your version of Windows from Microsoft.
2. Once the update finishes, restart your computer.
3. Install QuickBooks Desktop again.

If you can install and open QuickBooks, you're good to go. If you continue to see issues, you can repair specific Windows components yourself. You can seek assistance from an IT expert to perform the process:

• Repair or reinstall Microsoft .NET Framework
• Repair Microsoft MSXML

 Additionally, you install QuickBooks in Selective Startup mode to install QuickBooks smoothly.

Once you've installed QuickBooks, you can check out the references from this link as your guide while working with QuickBooks: Get started with QuickBooks Desktop.

If you have any other questions about QuickBooks installation, let me know by adding a comment below. I'm always here to help. Have a good one!