How do I stop QB pop-ups trying to sell me additional services or making suggestions about accepting online payments, etc. Extremely distracting and annoying.

I understand that the ads may affect your navigation. However, the option to disable them permanently is currently unavailable.

These ads aim to guide and suggest ways to optimize your QuickBooks Online experience. To remove the pop-ups from your QuickBooks homepage, kindly click on the X or No, thanks buttons.

Moreover, you may want to browse this page that contains helpful articles that can guide you in managing your QuickBooks account: QuickBooks Online Help Articles.

If you have any other questions, feel free to reach out. Stay safe.

In other words, there is NO way for you to turn them off or keep them from popping up, because even with the X or close, they will still pop up.  And QB has NO intensions of changing that.  They like to annoy their customer any way they can.  

Yes, @NinoNorth  just can't bring themselves to say it, but yes, there is no way to turn off the ads. Intuit likes it that way. They do not care that no one else likes it.

But hey, at least you get to pay a lot more for QB Online and get a lot less than when using QB Desktop. Isn't that nice?

"the option to disable them permanently is currently unavailable"  That answers my question.  We are forced to close popups whether we want them or not.

"To remove the pop-ups from your QuickBooks homepage, kindly click on the X or No, thanks buttons."  This is exactly what I should NOT have to do.  Intuit insults the customer by forcing popups in a software that we are paying for.

Today I am getting the popup for EVERY invoice I've created.  I have to X out of it, and then my invoice is still there and I have to save it again.  I called the helpdesk and they helpfully told me "no one can control them".  She doubled down that Intuit itself has no control over ads for THEIR products popping up in THEIR platform.  I've gotten the popups occasionally before, but today it is constant and I'm fed up.

Every single invoice.  Every single time.  This is happening to us, too.  Add in a slow network and productivity has ground to a halt.  Please fix this!

@KFib  RE: She doubled down that Intuit itself has no control over ads for THEIR products popping up in THEIR platform.

That's a lie.

@KFib My coworker just reported that he signed out and back in multiple times (out of frustration) and now he has the new invoice layout and the accept online payments pop-up has stopped.  Not rational but it worked.