Let me help and make sure you can update the address for your vendor in QuickBooks Desktop.
We can perform troubleshooting steps to fix unusual behavior in QuickBooks Desktop. To start, run the Verify Utility tool to check for errors.
Like this:
Go to QuickBooks File menu.
Choose Utilities, then Verify Data.
Select OK when you see the message QuickBooks detected no problem with your data. You may continue using your company file.
If Verify finds an issue with your data, you will be prompted to Rebuild Now or View Errors. Select Rebuild Now.
If you still see an error after running the Verify utility tool, you can run the Rebuild again. It's normal for a rebuild to be ran two or three times, as long as your error messages are changing without looping, it's working.
Here's how:
Go to QuickBooks File menu.
Select OK.
Follow the onscreen instruction to create the backup copy of your company file,
Click on OK.
Once you get the message Rebuild has completed, run the Verify utility tool again.